Isabel Mundry's work is characterized by a unique sonic language that investigates the relationships between time, space, and perception in rich, multi-faceted ways. In doing so, she creates new pathways and different realities in her compositions, which are explored through the timbre, harmony, and rhythms of her nuanced music.

Born in Hessen in 1963 and raised in Berlin, Isabel Mundry honed her composition skills under Frank Michael Beyer, Gösta Neuwirth, and Hans Zender, among others. This training was complemented by studies in musicology, art history, and philosophy, as well as a course in computer science and composition at the Paris IRCAM. After gaining attention in the 90s for her chamber music compositions and ensemble and orchestral works, her first music theatre work was a resounding success: in 2005, the premiere of Ein Atemzug – die Odyssee at the Deutsche Oper Berlin (Reinhild Hoffmann, staging; musical direction, Peter Rundel), was named best premiered work of the year by the magazine Opernwelt. In the work, the composer deals with layers of remembering and forgetting. Isabel Mundry’s interest in fusing musical structure to spatial presentation continued with Nicht Ich – über das Marionettentheater, a concert staged and conceived with the dancer and choreographer Jörg Weinöhl; it premiered in 2011 at the Kleistfestival in Thun in a performance by the Ensemble Recherche and the Vokalensemble Zürich and was subsequently shown in Zurich, Basel, Lyon, Dusseldorf, and Salzburg.

Isabel Mundry's numerous works for solo instruments and orchestras include Nocturno, first performed in 2006 by the Chicago Symphony Orchestra under Daniel Barenboim and later interpreted by the Staatskapelle Berlin and Dresden, the RSO Vienna and the Hamburg Philharmonic. Her piano concerto Ich und Du, which premiered at the Donaueschinger Musiktage 2008 with the SWR Symphony Orchestra under Pierre Boulez, later expanded into Non-Places, a piano concerto. For the 2013 Happy New Ears Prize award ceremony, the work was premiered by the Symphonieorchester des Bayerischen Rundfunks under Emilio Pomarico and it was subsequently awarded the German Music Authors' Prize by GEMA.

Among the world premieres of recent years are works of various genres with diverse sources of inspiration: in Vogelperspektiven for ensemble (world premiere 2016, Symphonieorchester des Bayerischen Rundfunks), inspired by poems by Thomas Kling, Isabel Mundry gives life to the changing perspectives of the human and animal worlds. Zu Fall, premiered by Tonhalle Orchester Zürich 2016, investigates the relationship between activity and passivity and features onstage as a shadow play a chaotically oscillating pendulum, which conducts the conductor as it pendulates. In Sounds, Archeologies, premiered by Trio Catch at Berlin's Ultraschall Festival in 2018 and most recently performed at the Wien Modern festival in 2023, she questions the proximity and distance of historical objects and cultural identities. And in the a-cappella choral piece Mouhanad, based on an interview with a Syrian refugee and premiered in Donaueschingen by the SWR Vokalensemble in 2018, cultural resonances and new acoustic neighborhoods are examined. 

In February 2020, Noli me tangere, her new work for percussion solo and ensemble, was premiered simultaneously at the final concert of the Festival Présences with Ensemble intercontemporain and in Cologne with Ensemble Musikfabrik. Further performances followed with the Collegium Novum Zurich and the Ensemble Arc-en-ciel. In 2022, Isabel Mundry was Artiste étoile of the Mozartfest Würzburg, during which Signaturen for two pianos, percussion and strings was premiered by the GrauSchumacher Piano Duo and Ensemble Resonanz. The Austrian premiere of the work took place at the Wien Modern festival; a further performance followed in February 2023 at the Elbphilharmonie. In 2022, Isabel Mundry was also Theme Composer of the Suntory Hall Summer Festival, where Nils Mönkemeyer and the Tokyo Symphony Orchestra under Michael Wendeberg premiered her viola concerto Gesture.

Isabel Mundry started the current season with lectures and concerts at the Ostrava Days festival, before appearing at the Mixtur festival in Barcelona, again with a lecture and concert as well as composition workshops. The focus of the current season was her composition Invisible, a spatial constellation about belonging, inclusion and exclusion. The highly acclaimed premiere by the vocal ensemble Exaudi and the Ensemble PHACE took place in November 2023 at the Wien Modern Festival, which also presented her works in concerts with the Arditti Quartet, among others. Performances of Endless Sediments for chamber orchestra are scheduled for June 2024 with the Basel Sinfonietta under Titus Engel at the Royal Danish Library in Copenhagen and at the Stadtkasino Basel.

Isabel Mundry's numerous awards and honours include the Kranichstein Music Prize in 1996, a 2001 Ernst von Siemens Music Foundation Composer Prize, and the 2011 Heidelberg Artists' Prize. In 2007/08 she was the Staatskapelle Dresden’s first Capell-Compositeur, composer-in-residence. Isabel Mundry is a member of the Academy of the Arts in Berlin and Munich as well as the Academy of Sciences and Literature in Mainz. Since 1998 she has been a frequent lecturer at the Darmstadt Summer Courses. After holding a professorship at the Frankfurt University of Music and Performing Arts from 1996, she has been a professor of composition at the Zurich University of the Arts since 2004 and, since 2011, a professor at the University of Music and Performing Arts Munich.